Analytical Testing
Morphology Analysis and Particle Sizing
time2018-06-01
1
Scanning Electron Microscope (SEM)
Characterization, Morphological and chemical analysis, Coating analysis, Elemental contents (qualitative analysis, quantitative analysis, composition along a line, map solution)
Powder and block solid
Scanning Electron Microscope (SEM) (Zeiss) – Energy Dispersive Spectrometer (EDS) (Oxford)
>> Technical Specifications: 1) Electron emission: tungsten filament; 2) Resolution: 3 nm @ 30 kV (SE); 3) Acceleration voltage: 0.2 to 30 kV; 4) Magnification:<5 – 1,000,000×
Microstructure & Morphology
JY/T 010-1996 General rules for analytical scanning electron microscopy
2
Shape and Size of Particles
Particle size and shape analysis, Particle size distribution
Suspensions, emulsions, dry powders
Laser Diffraction Particle Size Analyzer (Malvern)
>> Specifications: 1) Manual wet dispersion unit and automated dry powder dispersion unit; 2) Particle size range from 0.01 to 3500 μm; 3) Suitable for samples either in aqueous or non-aqueous dispersants
Particle Analyzer (Malvern)
>> Specifications: 1) Automated imaging for advanced particle characterization; 2) Integrated dry powder disperser option; 3） Particle size range from 0.5 μm to 1000 μm
3
Dynamic Light Scattering
Size distribution, translational diffusion coefficient Dt, diffusion interaction parameter kD, the second virial coefficient A2, solution viscosity in high concentration formulations
Proteins, samples or buffers with excipients such as pharmaceutical formulations
Dynamic Light Scattering (WYATT)
>> Specifications: 1) Laser: 658 nm; 2) Size range from 0.2 nm to 2500 nm in radius; 3) Molecular weight range from 300 Da to 1 MDa; 4) Minimal sample volume: 1 μL; 5) Concentration: 0.1 mg/mL 14 kDa Lysozyme; 6) Temperature range from −15°C to +150°C